Alpha Tau Treats First Patient with Advanced Inoperable Pancreatic Cancer at Israel’s Hadassah Medical Center

JERUSALEM, Sept. 14, 2023 (GLOBE NEWSWIRE) — Alpha Tau Medical Ltd. (“Alpha Tau”, or the “Company”) (NASDAQ: DRTS, DRTSW), the developer of the innovative alpha-radiation cancer therapy Alpha DaRT™, announced today that a patient with advanced inoperable pancreatic cancer has been treated in a clinical trial at Hadassah Medical Center in Jerusalem, Israel. The trial is designed for a broad range of solid tumor patients who do not qualify for participation in other existing trials or who do not have other treatment options according to the treating physician.

“We are dedicated to improving the lives and giving hope to cancer patients and their families, and we believe that Alpha DaRT has the potential to transform the treatment landscape for malignant tumors worldwide,” said Alpha Tau CEO Uzi Sofer. “Treating this patient with advanced inoperable pancreatic cancer, who may not have had other life-saving options at this stage, is very encouraging as we continue to execute on our unwavering mission to reach those patients with high unmet need. We are pursuing our objective of establishing Alpha DaRT as a treatment option for this terrible illness with our ongoing studies of pancreatic cancer in Israel and Montreal.”

“The Department of Gastroenterology of Hadassah University Medical Center, in conjunction with all our multidisciplinary partners, was privileged to utilize the groundbreaking Israeli technology of endoscopic ultrasound-guided implantable alpha radiation to treat a patient with pancreatic cancer,” noted Dr. Harold Jacob, Head of the Advanced Endoscopic Unit, Hadassah Medical Center, who, together with Dr. Ari Benson and Dr. Julia Epstein, treated the patient. “The procedure was smooth, straightforward, and incredibly quick, thanks to the support of the Alpha Tau team. The Alpha DaRT treatment holds promise and gives hope for pancreatic cancer patients and their families.”

“Pancreatic cancer is particularly devastating, with an estimated 5-year survival rate of less than 5%,” commented Alpha Tau CMO Dr. Robert Den. “Alpha DaRT might offer hope to patients who otherwise may not have available efficacious treatments. I am heartened that we have been able to treat our first pancreatic cancer patient in Israel, and I look forward to gaining further insight into the safety and efficacy profile of Alpha DaRT from our ongoing studies.”

About Alpha Tau Medical Ltd.

Founded in 2016, Alpha Tau is an Israeli medical device company that focuses on research, development, and potential commercialization of the Alpha DaRT for the treatment of solid tumors. The technology was initially developed by Prof. Itzhak Kelson and Prof. Yona Keisari from Tel Aviv University.

About Alpha DaRT™

Alpha DaRT (Diffusing Alpha-emitters Radiation Therapy) is designed to enable highly potent and conformal alpha-irradiation of solid tumors by intratumoral delivery of radium-224 impregnated sources. When the radium decays, its short-lived daughters are released from the sources and disperse while emitting high-energy alpha particles with the goal of destroying the tumor. Since the alpha-emitting atoms diffuse only a short distance, Alpha DaRT aims to mainly affect the tumor, and to spare the healthy tissue around it.